Virginia opossums may be predated upon by owls, dogs, coyotes, foxes, raccoons, bobcats, snakes, and humans, but are immune to the venom of a variety of snakes from the family, Viperidae.
Virginia opossums may be predated upon by a variety of species including owls, domestic dogs, coyotes, red foxes, raccoons, bobcats and large snakes, among others. They may also be hunted or trapped by humans.
Virginia opossums are immune to the venom of a variety of snakes from the family, Viperidae, including eastern and western diamondback rattlesnakes, copperheads, cottonmouth moccasins and Korean mamusi.
The opossum may have a better chance of survival within more urban environments due partially to the lower predation risk.