Slender-snouted crocodile eggs and hatchlings are preyed on by otters, leopards, various birds and rodents, and even other crocodiles.
Predation on crocodilians occurs mainly at the egg or hatchling stage. Various animals feed on the eggs of slender-snouted crocodiles, including spotted-necked otters (Hydrictis maculicollis), leopards (Panthera pardus), and various bird and rodent species. Recent hatchlings face many of the same predators, as well as potential cannibalism by larger conspecifics.
The large size and heavy scales of adults likely protects them from predation by other species, with the exception of humans, who hunt slender-snouted crocodiles for their skin and meat.