Little is known regarding the reproduction of Annamite striped rabbits as few individuals have been observed, but their thought to have maternal parental investment.
Almost nothing is known regarding the reproduction of Annamite striped rabbits or its sister species, Sumatran striped rabbits (Nesolagus netscheri), as few individuals have been observed.
As mammals, mother Annamite striped rabbits are assumed to provide nourishment until weaning.
A duo of kittens, estimated to be approximately one week old, was found in a shallow burrow in Phou Chomvoy Provincial Protected Area, Bolikhamxai province, Lao PDR, during the month of January. A second duo of kittens, estimated to be 10–12 weeks of age, were found in Pu Mat NP in the month of May.